2(1H)-Pyrimidinone, 5-acetyl-4-methyl-

2(1H)-Pyrimidinone, 5-acetyl-4-methyl- - Names and Identifiers

Name	2(1H)-Pyrimidinone, 5-acetyl-4-methyl-
Synonyms	5-acetyl-4-methyl-3H-pyrimidin-2-one 5-Acetyl-4-MethylpyriMidin-2(1H)-one 5-Acetyl-4-methyl-2(1H)-pyrimidinone 5-acetyl-4-methylpyrimidin-2(1H)-one 2(1H)-Pyrimidinone, 5-acetyl-4-methyl- 5-ethanoyl-4-methyl-3H-pyrimidin-2-one 2(1H)-PyriMidinone, 5-acetyl-6-Methyl- 2(1H)-Pyrimidinone, 5-acetyl-4-methyl- (9CI) 5-acetyl-4-Methyl-1,2-dihydropyriMidin-2-one
CAS	113246-41-6

2(1H)-Pyrimidinone, 5-acetyl-4-methyl- - Physico-chemical Properties

Molecular Formula	C7H8N2O2
Molar Mass	152.15
Density	1.28±0.1 g/cm3(Predicted)
pKa	8.45±0.10(Predicted)
Storage Condition	2-8°C

2(1H)-Pyrimidinone, 5-acetyl-4-methyl- - Introduction

4-Methyl-5-acetylpyrimidin-2-one is an organic compound with the chemical formula C9H10N2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
4-Methyl-5-acetylpyrimidin-2-one is a white crystalline solid, soluble in alcohol and ketone solvents. It has a moderate melting and boiling point and is stable in air. The molecular weight of this compound is small, and its structure contains methyl groups, acetyl groups and pyrimidine rings, making it widely used in organic synthesis.

Use:
4-methyl -5-acetyl pyrimidin-2-one is commonly used as a pharmaceutical intermediate, which can be used to synthesize a variety of bioactive molecules, such as anti-cancer drugs, antiviral drugs, etc. It can also be used in the synthesis of dyes, solvents and catalysts for organic reactions.

Preparation Method:
4-Methyl -5-acetyl pyrimidin-2-one is generally prepared by synthetic routes. The common method is to use 2,4-lutidine as raw material, through formaldehyde hydroxymethylation reaction to generate 4-methyl -5-formaldehyde pyrimidin-2-one, and then carry out acetylation reaction to obtain the target product.

Safety Information:
When using 4-methyl-5-acetylpyrimidin-2-one, it is necessary to pay attention to follow laboratory safety operations and personal protective measures. This compound may be toxic and irritating and direct contact with skin and eyes should be avoided. At the same time, during storage and transportation, it is necessary to keep away from high temperature, fire source and oxidant. To ensure safe use, please read the safety data sheets (MSDS) of the relevant chemicals carefully.

Last Update：2024-04-09 21:11:58